Lyophilization Technology

Project Directors

Edward Trappler"What makes LTI unique is our group who appreciate how significant it is having an important product available for the benefit of patients. It is inspiring to collaborate with dedicated and talented scientists and staff that make extraordinary things happen." - Edward H. Trappler, President
MEET OUR LEADERSHIP TEAM

Michael Thomas, Senior Research Scientist, Project Director

Mike Thomas, Senior Research Scientist and Project Director, has been with LTI for over 16 years. He is responsible for project coordination from concept through clinical manufacturing, including, product and process development, technical support, troubleshooting, and clinical trial material manufacturing. Mike’s technical focus is product design in novel container closure delivery systems such as dual chamber cartridges and syringes.

Mike started with LTI in 2001 as a Research Technician. Over the years he was promoted to Associate Scientist, Research Scientist, and then his current role as Senior Research Scientist. Mike is also a member of the LTI Scientific Advisory Board.

Mike received his Bachelor of Science in Biology from Arcadia University. He is currently pursuing his Masters in Pharmaceutics from Temple University. He has been published in Pharmaceutical Technology and has authored and presented podium and poster presentations to the industry.

Amy M. Bosch, Associate Scientist, Project Director

Amy Bosch, Associate Scientist and Project Director, has been with LTI for over 12 years. As an Associate Scientist and Project Director, she is responsible for project coordination from concept through clinical manufacturing, including product and process development, technical support, troubleshooting, and clinical trial material manufacturing. Amy's technical focus is Finished Product Testing.

Amy began her career with LTI in 2004 as a Technician. Over the years, she was promoted to Senior Technician, Research Technician and to her current role as Associate Scientist in 2007. Prior to joining LTI she held a position at GlaxoSmithKline.

Amy received her Bachelor of Sciences in Biology from Millersville University in Biology. She has authored and presented numerous poster presentations for the industry and has given lectures on Critical Quality Attributes of Lyophilized Products.

Andrew M. Smith, Associate Scientist, Project Director

Andrew Smith, Associate Scientist and Project Director, has been with LTI for over 10 years. As an Associate Scientist and Project Director, he is responsible for project coordination from concept through clinical manufacturing, including product and process development, technical support, troubleshooting, and clinical trial material manufacturing. He is also lead Project Director for Thermal Analysis studies.

Andrew began his career at LTI as a Development Technician I in 2007. Over the years, he has been promoted to Development Technician II, III, Technical Associate, and to his current role as Associate Scientist in 2016. Prior to joining LTI, Andrew held internship positions at NASA and Elan NanoSystems.

Andrew received his Bachelor of Science in Biomedical Engineering, with a concentration in Tissue Engineering and Biomaterials from Drexel University. He has authored and presented poster presentations at focused industry events.

Timothy Dutill, Research Scientist, Project Director

Tim Dutill, Research Scientist and Project Director, has been with LTI for over 6 years. He is responsible for project coordination from concept through clinical manufacturing, including product and process development, technical support, troubleshooting, and clinical trial material manufacturing. Tim's focused activities include understanding the control of heat transfer inside the lyophilizer through shelf temperature mapping and sublimation studies. He also holds the position of Safety Officer at LTI.

In 2011, Tim started with LTI as an Associate Scientist and Project Director. He was promoted to Research Scientist in 2014. Prior to LTI, Tim began his career in the vaccine field as a Product Development Scientist at the Infectious Disease Research Institute (IDRI).

Tim received his Bachelor of Science in Chemical Engineering from Pennsylvania State University. He has been published in the Journal of Colloids and Surfaces B: Biointerfaces, Pharmaceutical Development and Technology and Biopharm International.

John M. Stewart, Associate Scientist, Project Director

John Stewart joined LTI as an Associate Scientist and Project Director in August 2016. He is responsible for project coordination from concept through clinical manufacturing, including product and process development, technical support, troubleshooting, and clinical trial material manufacturing. John's technical focus is dual chamber cartridge processing and containment via the use of isolators.

John has more than 6 years of pharmaceutical research experience. Prior to joining LTI, John held a position in the Department of Formulation Sciences at MedImmune, where he was in charge of planning experiments for early stage development, and lyophilization process development.

John received his Bachelor of Science degree in Biotechnology from Delaware State University. In 2013, John received his Masters of Science degree in Pharmaceutical Chemistry from the University of Kansas. He has been published in the Journal of Pharmaceutical Chemistry, Journal of Molecular Pharmaceutics, and Journal of Clinical and Experimental Immunology.