Lyophilization Technology

Posters

Our Scientific Advisory Board oversees our internal research activities and provides guidance to our scientific staff. While engaging in continued research for greater knowledge and to promote technological developments, our goal is to also provide you a better understanding by publishing and presenting our discoveries for educational purposes. Below is a list of LTI's posters authored by our staff which have been presented to the pharmaceutical community, professional organizations, and industry events within the United States and internationally. Should you be interested in reviewing a copy of any of the items listed, please contact us and we will be happy to assist you. If you would like to receive insider announcements of our latest research presented to the industry you may subscribe to receive our "In the Know" newsletter.

  • Combining Nucleation Technology and Aseptic Processing: The Impact of ControLyo™ on the Viability and Performance of Process Simulation Media Fills
  • Comparative Methods of Measurement and the Effect of Reduced Pressure on Seal Integrity for Lyophilized Products (PDA)
  • Contributing Factors to Lyophilizer Shelf Edge Effect and its Impact on Heat Transfer to the Product (AAPS)
  • Effect of Amorphous and Crystalline Solutes on the Low Temperature Crystallization of Proline (AAPS)
  • Effect on Container/Closure, Solute and Processing Parameters on Relative Rates of Sublimation During Primary Drying (CPPR Conference on Freeze Drying of Pharmaceuticals and Biologicals)
  • Effects of the Vial on Sublimation Rates w/ Ulfik, The Virtis Company (PDA)
  • Evaluating Lyophilized Product Appearance in a Laboratory Setting (CHI PepTalk)
  • Evaluating the Impact of Controlled Nucleation on Finished Product Attributes of Bulk Lyophilized Material (CHI Peptalk)
  • Evaluating the Impact of Controlled Nucleation on Lyophilized Product Attributes and Processing Characteristics in an Aseptic Environment (CHI PepTalk)
  • Evaluating the Impact of Controlled Nucleation on Processing Bulk Lyophilized Material (CHI PepTalk)
  • Identification of Glass Vial Features Infuencing Heat Transfer as Measured by Sublimation Rate Using a Placket Burman Design w/ Asselta, Comar (CPPR Conference on Freeze Drying of Pharmaceuticals and Biologicals)
  • Identifying TPPs and Establishing CQAs to Support Commercial Product Specifications (DIA, CPPR)
  • Impact of Lyophilizer Vacuum Pump Capacity and Gas Bleed Port Location on the Sublimation of Ice (AAPS)
  • Impact of Variable on Sublimation Rate Study Design (AAPS)
  • Importance of Identifying TPPs and Establishing CQAs for a Lyophilized Parenteral (PDA)
  • Influence of Vial Construction and Material on Uniformity of Product Temperature During Freezing and Freeze Drying of Model Product Formulations w/ The West Company (PDA)
  • Lyophilization in Plastic vs. Glass Syringes and Cartridges (CHI PepTalk)
  • Lyophilization Process Evaluation in Dual Chamber Cartridge Dosage Forms for Achieving Preferred Product Presentation and Batch Uniformity
  • Lyophilization Process Evaluation in Various Dual Chamber Cartridge Dosage Forms for Production Flexibility (PDA)
  • A Method for Combatting Temperature Non-Uniformity within the Lyophilizer... and Win (AAPS)
  • Methods for Evaluating the Variation in Heat Transfer for Tubing Vials (PDA)
  • Method for Evaluating Lyophilized Product in a Laboratory Setting (PDA)
  • Physical Strength of Materials for Pharmaceutical Vials and Prevention of Vial Breakage During Freezing and Freeze Drying w/ The West Company (PDA)
  • Process Validation for Lyophilized Drug Products: Developing a Program for Continued Process Verification (1st Year of Data) (PDA)
  • Process Validation for Lyophilized Drug Products: Developing a Program for Continued Process Verification (2nd Year of Data) (AAPS)
  • Quality Metrics for Contract Clinical Supply Operations (PDA)
  • Quality Systems for Contract Clinical Supply Operations: Using Risk Analysis to Meet Global Requirements (AAPS)
  • Understanding the Performance of a Lyophilizer Through Shelf Temperature Mapping Studies: Improving Technology Transfer Results (PDA)
  • Vials and Prevention of Vial Breakage During Freezing and Freeze Drying w/ The West Company (PDA)